Opteron 8216 HE (F3) 's Advantages
Lower TDP (68W vs 170W)
AMD EPYC 7371 's Advantages
Released 12 years and 3 months late
Higher specification of memory (2666 vs 667)
Newer PCIe version (3 vs 1)
Higher base frequency (3.1GHz vs 2.4GHz)
More modern manufacturing process (14nm vs 90nm)