AMD EPYC 7272 's Advantages
Lower TDP (120W vs 290W)
AMD EPYC 9454 's Advantages
Released 3 years and 3 months late
Higher specification of memory (4800 vs 3200)
Newer PCIe version (5 vs 4)
Higher base frequency (2.75GHz vs 2.6GHz)
Larger L3 cache size (256MB vs 64MB)
More modern manufacturing process (5nm vs 7nm)