AMD EPYC 7272 's Advantages
Larger L3 cache size (64MB vs 24MB)
More modern manufacturing process (7nm vs 10nm)
Xeon E 2488 's Advantages
Released 4 years and 4 months late
Higher specification of memory (4800 vs 3200)
Newer PCIe version (5 vs 4)
Higher base frequency (3.2GHz vs 2.6GHz)
Lower TDP (95W vs 120W)