AMD EPYC 7281 's Advantages
Larger L3 cache size (32MB vs 24MB)
Lower TDP (170W vs 250W)
Intel Xeon W 3335 's Advantages
Released 4 years and 1 months late
Higher specification of memory (3200 vs 2666)
Newer PCIe version (4 vs 3)
Higher base frequency (3.4GHz vs 2.1GHz)
More modern manufacturing process (10nm vs 14nm)