AMD EPYC 7443 's Advantages
Released 14 years and 7 months late
Higher specification of memory (DDR4-3200 vs DDR2-667)
Newer PCIe version (4 vs 1)
Higher base frequency (2.85GHz vs 2.4GHz)
More modern manufacturing process (7nm vs 90nm)
Opteron 8216 (F3) 's Advantages
Lower TDP (95W vs 200W)