AMD EPYC 7451 's Advantages
Higher base frequency (2.3GHz vs 2.25GHz)
Lower TDP (180W vs 500W)
AMD EPYC 9965 's Advantages
Released 7 years and 4 months late
Higher specification of memory (6000 vs 2666)
Newer PCIe version (5 vs 3)
Larger L3 cache size (384MB vs 64MB)
More modern manufacturing process (3nm vs 14nm)