AMD EPYC 7451 's Advantages
Released 10 years and 10 months late
Higher specification of memory (2666 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)
Opteron 2216 HE (F2) 's Advantages
Higher base frequency (2.4GHz vs 2.3GHz)
Lower TDP (68W vs 180W)