AMD EPYC 7451 's Advantages
Lower TDP (180W vs 250W)
Xeon 6740E 's Advantages
Released 7 years late
Higher specification of memory (6400 vs 2666)
Newer PCIe version (5 vs 3)
Higher base frequency (2.4GHz vs 2.3GHz)
Larger L3 cache size (96MB vs 64MB)
More modern manufacturing process (5nm vs 14nm)