AMD EPYC 7453 's Advantages
Released 9 years late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (64MB vs 10MB)
More modern manufacturing process (7nm vs 32nm)
Intel Xeon E5 2643 's Advantages
Higher base frequency (3.3GHz vs 2.75GHz)
Lower TDP (130W vs 225W)