AMD EPYC 7543 's Advantages
Released 8 years and 3 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)
Opteron 3350 HE 's Advantages
Lower TDP (45W vs 225W)