AMD EPYC 7642 's Advantages
Released 12 years and 6 months late
Higher specification of memory (3200 vs 2)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)
Opteron 2220 's Advantages
Higher base frequency (2.8GHz vs 2.4GHz)
Lower TDP (95W vs 225W)