AMD EPYC 7643 's Advantages
Released 9 years and 4 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.3GHz vs 2.1GHz)
Larger L3 cache size (256MB vs 16MB)
More modern manufacturing process (7nm vs 32nm)
Opteron 6272 's Advantages
Lower TDP (115W vs 225W)