AMD EPYC 7663 's Advantages
Released 14 years and 7 months late
Higher specification of memory (DDR4-3200 vs DDR2-667)
Newer PCIe version (4 vs 1)
More modern manufacturing process (7nm vs 90nm)
Opteron 8220 SE (F2) 's Advantages
Higher base frequency (2.8GHz vs 2GHz)
Lower TDP (120W vs 240W)