AMD EPYC 9534 's Advantages
Released 10 years late
Higher specification of memory (4800 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (2.45GHz vs 2.4GHz)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)
Opteron 6378 's Advantages
Lower TDP (115W vs 280W)