AMD EPYC 9645 's Advantages
Released 5 years and 10 months late
Higher specification of memory (6000 vs 4)
Higher base frequency (2.3GHz vs 2.2GHz)
Larger L3 cache size (256MB vs 22MB)
More modern manufacturing process (3nm vs 14nm)
Xeon Platinum 8253 's Advantages
Lower TDP (125W vs 320W)