Intel Xeon E3 1280 v2 's Advantages
Higher base frequency (3.6GHz vs 2.6GHz)
Intel Xeon E 2378 's Advantages
Released 9 years and 4 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (16MB vs 8MB)
More modern manufacturing process (14nm vs 22nm)
Lower TDP (65W vs 69W)