Intel Xeon E3 1280 v2 's Advantages
Higher base frequency (3.6GHz vs 3.1GHz)
Lower TDP (69W vs 205W)
Intel Xeon Gold 6346 's Advantages
Released 8 years and 11 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 3)
Larger L3 cache size (36MB vs 8MB)
More modern manufacturing process (10nm vs 22nm)