Intel Xeon E3 1280 v2 's Advantages
Higher base frequency (3.6GHz vs 2.2GHz)
Lower TDP (69W vs 270W)
Intel Xeon Gold 6454S 's Advantages
Released 10 years and 8 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (60MB vs 8MB)
More modern manufacturing process (10nm vs 22nm)