Intel Xeon E3 1280 's Advantages
Higher base frequency (3.5GHz vs 2GHz)
Lower TDP (95W vs 300W)
Intel Xeon Platinum 8452Y 's Advantages
Released 11 years and 9 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (67.5MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)