Intel Xeon E5 2680 's Advantages
Higher base frequency (2.7GHz vs 2.5GHz)
Lower TDP (130W vs 205W)
Intel Xeon Platinum 8180M 's Advantages
Released 5 years and 4 months late
Higher specification of memory (DDR4 vs DDR3)
Larger L3 cache size (38.5MB vs 20MB)
More modern manufacturing process (14nm vs 32nm)