Intel Xeon E5 4640 's Advantages
Higher base frequency (2.4GHz vs 2GHz)
Lower TDP (95W vs 300W)
Intel Xeon Platinum 8452Y 's Advantages
Released 10 years and 8 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 3)
Larger L3 cache size (67.5MB vs 20MB)
More modern manufacturing process (10nm vs 32nm)