Intel Xeon E5640 's Advantages
Higher base frequency (2.666GHz vs 2.2GHz)
Lower TDP (80W vs 270W)
Intel Xeon Gold 6454S 's Advantages
Released 12 years and 10 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (60MB vs 12MB)
More modern manufacturing process (10nm vs 32nm)