Intel Xeon E5645 's Advantages
Higher base frequency (2.4GHz vs 2GHz)
Lower TDP (80W vs 150W)
Intel Xeon Gold 5416S 's Advantages
Released 12 years and 10 months late
Higher specification of memory (4400 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (30MB vs 12MB)
More modern manufacturing process (10nm vs 32nm)