Intel Xeon E5645 's Advantages
Higher base frequency (2.4GHz vs 1.9GHz)
Lower TDP (80W vs 350W)
Intel Xeon w9 3495X 's Advantages
Released 12 years and 11 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (105MB vs 12MB)
More modern manufacturing process (10nm vs 32nm)