Opteron 2216 HE (F3) 's Advantages
Lower TDP (68W vs 320W)
AMD EPYC 9184X 's Advantages
Released 16 years and 10 months late
Higher specification of memory (DDR5-4800 vs DDR2)
Newer PCIe version (5 vs 1)
Higher base frequency (3.55GHz vs 2.4GHz)
More modern manufacturing process (5nm vs 90nm)