Opteron 2218 (F2) 's Advantages
Higher base frequency (2.6GHz vs 1.8GHz)
Lower TDP (95W vs 185W)
Intel Xeon Gold 6421N 's Advantages
Released 16 years and 5 months late
Higher specification of memory (4400 vs 2)
Newer PCIe version (5 vs 1)
More modern manufacturing process (10nm vs 90nm)