Opteron 2218 (F3) 's Advantages
Lower TDP (95W vs 180W)
AMD EPYC 72F3 's Advantages
Released 14 years and 7 months late
Higher specification of memory (3200 vs 2)
Newer PCIe version (4 vs 1)
Higher base frequency (3.7GHz vs 2.6GHz)
More modern manufacturing process (7nm vs 90nm)