Opteron 2218 (F3) 's Advantages
Lower TDP (95W vs 205W)
Xeon Platinum 8280M 's Advantages
Released 12 years and 4 months late
Higher specification of memory (2933 vs 2)
Newer PCIe version (3 vs 1)
Higher base frequency (2.7GHz vs 2.6GHz)
More modern manufacturing process (14nm vs 90nm)