Opteron 2222 's Advantages
Higher base frequency (3GHz vs 1.9GHz)
Lower TDP (95W vs 115W)
Opteron 6168 's Advantages
Released 2 years and 7 months late
Higher specification of memory (3 vs 2)
Newer PCIe version (2 vs 1)
More modern manufacturing process (45nm vs 90nm)