Opteron 2222 's Advantages
Higher base frequency (3GHz vs 2.2GHz)
Lower TDP (95W vs 105W)
Xeon E5 2650 v4 's Advantages
Released 8 years and 7 months late
Higher specification of memory (2133 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)