Opteron 2222 's Advantages
Higher base frequency (3GHz vs 2.7GHz)
Lower TDP (95W vs 205W)
Xeon Platinum 8280M 's Advantages
Released 11 years and 4 months late
Higher specification of memory (2933 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)