Opteron 2224 SE 's Advantages
Higher base frequency (3.2GHz vs 2.1GHz)
Lower TDP (119W vs 120W)
AMD EPYC 7251 's Advantages
Released 9 years and 10 months late
Higher specification of memory (2400 vs 2)
Newer PCIe version (3 vs 1)
More modern manufacturing process (14nm vs 90nm)