Opteron 3350 HE 's Advantages
Higher base frequency (2.8GHz vs 2.75GHz)
Lower TDP (45W vs 290W)
AMD EPYC 9454 's Advantages
Released 9 years and 11 months late
Higher specification of memory (4800 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)