Opteron 3350 HE 's Advantages
Higher base frequency (2.8GHz vs 2.1GHz)
Lower TDP (45W vs 225W)
Intel Xeon Gold 6448Y 's Advantages
Released 10 years and 1 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (60MB vs 8MB)