Opteron 3350 HE 's Advantages
Higher base frequency (2.8GHz vs 2.2GHz)
Lower TDP (45W vs 330W)
Xeon 6780E 's Advantages
Released 11 years and 6 months late
Higher specification of memory (6400 vs 3)
Newer PCIe version (5 vs 2)
Larger L3 cache size (108MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)