Opteron 3380 's Advantages
Released 6 years and 4 months late
Higher specification of memory (3 vs 2)
Newer PCIe version (2 vs 1)
More modern manufacturing process (32nm vs 90nm)
Lower TDP (65W vs 119W)
Opteron 2220 SE (F3) 's Advantages
Higher base frequency (2.8GHz vs 2.6GHz)