Opteron 4376 HE 's Advantages
Lower TDP (65W vs 320W)
AMD EPYC 9374F 's Advantages
Released 9 years and 11 months late
Higher specification of memory (DDR5-4800 vs DDR3)
Higher base frequency (3.85GHz vs 2.6GHz)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)