Opteron 6274 's Advantages
Lower TDP (115W vs 225W)
AMD EPYC 7453 's Advantages
Released 9 years and 4 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.75GHz vs 2.2GHz)
Larger L3 cache size (64MB vs 16MB)
More modern manufacturing process (7nm vs 32nm)