Opteron 6276 's Advantages
Lower TDP (115W vs 170W)
AMD EPYC 7351 's Advantages
Released 5 years and 7 months late
Higher specification of memory (2666 vs 3)
Newer PCIe version (3 vs 2)
Higher base frequency (2.4GHz vs 2.3GHz)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (14nm vs 32nm)