Opteron 6278 's Advantages
Lower TDP (115W vs 280W)
AMD EPYC 7573X 's Advantages
Released 9 years and 10 months late
Higher specification of memory (3200 vs 3)
Newer PCIe version (4 vs 2)
Higher base frequency (2.8GHz vs 2.4GHz)
Larger L3 cache size (768MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)