Opteron 6278 's Advantages
Higher base frequency (2.4GHz vs 2.1GHz)
Lower TDP (115W vs 150W)
Intel Xeon Gold 5318N 's Advantages
Released 8 years and 11 months late
Higher specification of memory (DDR4-2667 vs DDR3)
Newer PCIe version (4 vs 2)
Larger L3 cache size (36MB vs 8MB)