Opteron 6348 's Advantages
Lower TDP (115W vs 280W)
AMD Ryzen Threadripper PRO 5945WX 's Advantages
Released 9 years and 4 months late
Higher specification of memory (3200 vs 1866)
Newer PCIe version (4 vs 2)
Higher base frequency (4.1GHz vs 2.8GHz)
Larger L3 cache size (64MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)