Opteron 6366 HE 's Advantages
Lower TDP (85W vs 320W)
AMD EPYC 9274F 's Advantages
Released 10 years late
Higher specification of memory (4800 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (4.05GHz vs 1.8GHz)
Larger L3 cache size (256MB vs 8MB)
More modern manufacturing process (5nm vs 32nm)