Opteron 6378 's Advantages
Lower TDP (115W vs 185W)
Xeon w3 2535 's Advantages
Released 11 years and 9 months late
Higher specification of memory (4400 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (3.5GHz vs 2.4GHz)
Larger L3 cache size (26.25MB vs 8MB)
More modern manufacturing process (10nm vs 32nm)