Opteron 6380 's Advantages
Higher base frequency (2.5GHz vs 2.4GHz)
Lower TDP (115W vs 155W)
AMD EPYC 7352 's Advantages
Released 6 years and 9 months late
Higher specification of memory (3200 vs 1866)
Newer PCIe version (4 vs 2)
Larger L3 cache size (128MB vs 8MB)
More modern manufacturing process (7nm vs 32nm)