Opteron 6380 's Advantages
Lower TDP (115W vs 500W)
AMD EPYC 9755 's Advantages
Released 11 years and 11 months late
Higher specification of memory (6000 vs 1866)
Newer PCIe version (5 vs 2)
Higher base frequency (2.7GHz vs 2.5GHz)
Larger L3 cache size (512MB vs 8MB)
More modern manufacturing process (4nm vs 32nm)