Opteron 8216 (F2) 's Advantages
Lower TDP (95W vs 120W)
AMD EPYC 7272 's Advantages
Released 13 years late
Higher specification of memory (3200 vs 667)
Newer PCIe version (4 vs 1)
Higher base frequency (2.6GHz vs 2.4GHz)
More modern manufacturing process (7nm vs 90nm)