Opteron 8216 HE (F3) 's Advantages
Higher base frequency (2.4GHz vs 2GHz)
Lower TDP (68W vs 120W)
AMD EPYC 8224PN 's Advantages
Released 17 years and 1 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)