Opteron 8218 (F3) 's Advantages
Lower TDP (95W vs 290W)
AMD EPYC 9454 's Advantages
Released 16 years and 3 months late
Higher specification of memory (4800 vs 667)
Newer PCIe version (5 vs 1)
Higher base frequency (2.75GHz vs 2.6GHz)
More modern manufacturing process (5nm vs 90nm)