Opteron 8218 (F3) 's Advantages
Higher base frequency (2.6GHz vs 2.4GHz)
Lower TDP (95W vs 250W)
Xeon 6740E 's Advantages
Released 17 years and 10 months late
Higher specification of memory (6400 vs 667)
Newer PCIe version (5 vs 1)
More modern manufacturing process (5nm vs 90nm)